The Role of Lifestyle and Dietary Factors in the Development of Premature Ovarian Insufficiency

Premature ovarian insufficiency (POI) is a condition that arises from dysfunction or early depletion of the follicle pool accompanied by an earlier-than-normal loss fertility in young women. Oxidative stress has been suggested as important factor decline women and POI. In this review, we discuss mechanisms oxidative implicated ageing relation to POI, particular mitochondrial dysfunction, apoptosis inflammation. Genetic defects, autoimmunity chemotherapy, are some reviewed hallmarks POI can lead increased stress. Additionally, highlight lifestyle factors, including diet, low energy availability BMI, increase risk The final section review discusses dietary factors associated with consumption oily fish, mitochondria nutrient therapy, melatonin, dairy vitamins be targeted potential interventions, especially for at-risk combination personalised nutrition. Understanding impact its implications holds great promise reducing burden condition.